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Effects of tirzepatide, a dual GIP and GLP-1 receptor agonist, on blood pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats

10.2337/db15-0443 32 IshikawaM.NakazawaT.KunikataH.SatoK.YoshitomiT.KrishnanK.et al (2022)

Glucagonlike peptide1 treatment delays the onset of diabetes in 8 weekold db/db mice

Clinicians are also cautious about prescribing these drugs to individuals with a history of eating disorders, where appetite suppression and weight loss may trigger relapse

Obesity is a risk factor for a broad spectrum of diseases, including cardiovascular disease

These influences include geographic factors like access to healthy food, green space, and healthcare, as well as socioeconomic status, chronic stress, discrimination, and environmental pollution