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A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion

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Preclinical studies have indicated that GLP1RAs, such as tirzepatide, may directly impact the vasculature by enhancing endothelial function and decreasing inflammation, which are important in preventing atherosclerosis[30]

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Victoza (liraglutide) prescribing information

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Hematoxylin and eosin (H&E) and Massons trichrome staining were applied to these sections to evaluate inflammation and fibrosis

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Tirzepatide also acts on GIP receptors, which makes it mechanistically different

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J Phys Act Health 2016

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