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GLP-1 medications such as Ozempic and Wegovy have helped many people achieve significant weight loss and better overall health
In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.

As the fast ended for surgery rather than intolerance, research into longer water fasts could be considered.

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