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We recently encountered a similar case at our institution - a 49-year-old woman with type 2 diabetes, obesity, and chronic pain on long-term narcotic therapy, who presented with abdominal distension and vomiting after two years of tirzepatide (Mounjaro) therapy

Some studies have shown GLP-1 levels, particularly after meals, are lower in people with obesity

Key Nutrition Priorities on GLP-1 Nutrition on GLP-1 medications is not only about eating less

Injection site selection and rotation Where you inject matters as much as how you inject

Keep a simple mood log, even just a daily score out of ten, to spot trends early

The blood pressure-lowering effect may be partly mediated by weight loss, though other mechanisms may also contribute