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Monami, M

Investigators noted heart rate increased with tirzepatide relative to placebo therapy, with increases of 2.1 (95% CI, 0.3 to 3.9), 2.3 (95% CI, 0.6 to 4.1), and 5.4 (95% CI, 3.6 to 7.1) beats per minute, respectively, with tirzepatide 5, 10, and 15 mg at week 36 compared to baseline

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A lack of investment from the pharmaceutical industry has also stalled research

Exercise caution with medications requiring rapid gastrointestinal absorption or those with a narrow therapeutic index

Most SSRIs can generally be used with tirzepatide without direct interaction, with shared nausea being the main overlap