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Diabetologia (2011) 54:137987

Recent studies have indicated that the protective properties against endothelial dysfunction, anti-inflammatory effects on macrophages and the anti-proliferative action on smooth muscle cells may contribute to atheroprotection through GLP-1R signaling

The neurons in this area are mostly dopaminergic neurons that contain either dopamine 1 receptors or dopamine 2 receptors

JW: Formal analysis, Funding acquisition, Writing original draft

As oral NMN administration augments GLP-1 secretion and improves postprandial glucose metabolism in obese mice [31], the different effects between NMN and NR on GLP-1 production and whole-body glucose metabolism may involve the presence of the NMN transporter in the small intestine [175]
