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Most of the reproductive benefits observed in the trials are likely indirect mediated through weight loss and metabolic improvement rather than a direct drug effect on reproductive biology

doi: 10.14814/phy2.13503 34 SivertsenJRosenmeierJHolstJJVilsbllT

The efficacy of the vial can be compromised by 20%, 50% or more due to one large temperature excursion
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Life Sci 30:785791 Salem V, Izzi-Engbeaya C, Coello C et al (2016) Glucagon increases energy expenditure independently of brown adipose tissue activation in humans

Role of glucagon-like peptide (GLP-1) on vessel wall integrity The incretin hormone glucagon-like peptide-1 (GLP-1) is produced and secreted in the intestine upon food intake