downside of glp 1 drugs GLP-1 Agonists Explained: Definition, How They Work, Side Effects Variable weight-loss and cardiovascular benefits

2021 doi: 10.1111/bph.15508

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Most side effects are mild, like nausea or constipation, and usually decrease as treatment continues

Most clinical guidance recommends: At 3 months: A1c recheck (HbA1c reflects the prior 3-month average, making this the earliest timepoint for meaningful assessment of glycemic response), metabolic panel if any GI side effects were significant At 6 months: Full panel repeat A1c, CMP, lipids, CBC to document treatment response comprehensively Annually: Full panel plus thyroid function, B12, and any additional markers relevant to your individual health picture If you experience severe or persistent gastrointestinal side effects, signs of dehydration, unusual fatigue, or any concerning symptoms, kidney function should be rechecked without waiting for a scheduled interval

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