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But because GLP-1 medicationsincluding semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound)are relatively new and research is ongoing, experts advise against using them during pregnancy

however, the intracellular signalling mechanisms underlying these effects remain poorly defined

Referral to specialist services may be required, particularly for weight management indications

Disease-specific prioritization will be essential

NAFLD is associated with several comorbidities, including type 2 diabetes (T2D), cardiovascular diseases (CVD), and chronic kidney disease (CKD) 5

In November, the drugmaker received the FDAs Commissioners National Priority Voucher, a pilot program for accelerated drug review for companies supporting national interests, according to the FDA