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Description
GLP-1 is a hormone produced in the intestines that plays a crucial role in regulating blood sugar levels

International Agency for Research on Cancer Handbook Working Group

As previously mentioned, because DPP-4 inhibitors can increase the risk of hypoglycemia when added to insulin or a sulfonylurea, a dose decrease of sulfonylurea and/or insulin should be considered prior to initiation of a DPP-4 inhibitor

Liraglutide is a GLP-1 receptor agonist that acts by helping the pancreas to release the right amount of insulin when blood sugar levels are high

This pricing dynamic constrains overall market penetration and slows adoption despite the strong clinical benefits of GLP-1 therapies in weight management and glycemic control, making cost a key obstacle to broader global uptake

The decision, buried within the Department of Health Care Services (DHCS) cost-saving adjustments, comes after a year in which these drugs accounted for more than $1.6 billion in Medicaid reimbursements statewide
