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Retatrutide administered once weekly subcutaneously for 12 weeks resulted in a dose-dependent placebo-adjusted weight loss of up to 8.96 kg in the highest dose group and a placebo-adjusted HbA1c reduction of up to 1.6% in a phase II trial in individuals with T2DM [125]
As expected, in the responder group, body fat percentage was positively correlated with insulin resistance
Trllinger, Svenja Godbersen, Shahana Sengupta, Adrian Kaufmann, Sren Krogsgaard Thomsen, Bolette Hartmann, Yi-Chun Chen, Anna E
CNBC's Eunice Yoon and Paige Tortorelli contributed to this report.
