glp-1 antagonists GIPR antagonist antibodies conjugated to peptide are bispecific molecules that decrease weight in obese mice and monkeys: Cell Reports Medicine Frontiers | Exploring the multifaceted
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Montefusco L, DAddio F, Loretelli C, et al
A similar approach was successfully applied to develop selective drug activators of the protein kinase AMPK, which were revealed to bind to an unexpected allosteric site on AMPK that is distinct from the canonical AMP-binding sites [213,214,215,216]
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