retatrutide side effect skin tingling Two effects are showing up more often with than with other GLP-1 medications like semaglutide or tirzepatide: (paresthesias) and itching (pruritus). Even though retatrutide is still in research and The Retatrutide Dysesthesia Puzzle
Description
Fonseca V, Madsbad S, Falahati, Zychma MJ, Plutzky J
It is administered as a weekly subcutaneous injection, available in doses from 2.5 mg up to 15 mg, typically titrated upward over several months
Within hours of the first dose, all troublesome symptoms had substantially improved or resolved
Cell Death Dis (2013) 4:e612
But it doesn't have to be overwhelming, GoodRx says
10.1172/JCI143770 [DOI] [PMC free article] [PubMed] [Google Scholar] Borner, T
