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(2008) and Wild et al

GLP-1 medications can cause mood changes in some patients

Their effects on the individual components of MACE, myocardial infarction (reduced in LEADER and Harmony Outcomes), and stroke (reduced in SUSTAIN-6 and REWIND), varied in each trial (Table 1)

Preoperative planning requires particular attention: according to 2024 multi-society guidance (including the American Society of Anesthesiologists), most patients can continue GLP-1 receptor agonists perioperatively

Cutting phases increase injury risk through reduced recovery capacity, and these healing peptides can help manage soft tissue issues that might otherwise force training modifications

Each patient may lose weight at a different rate and experience different side effects
