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Understanding these distinctions helps Canadians navigate available options while remaining aware of associated considerations

Avoid taking the medication too early or doubling up on doses, as this can lead to complications

while glycaemic efficacy diminishes at lower eGFR levels, some agents are licensed for heart failure and chronic kidney disease at eGFRs below 30 ml/min/1.73m

Studies often investigate its role in glucose regulation pathways, energy expenditure mechanisms, and metabolic homeostasis

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For Regulatory Affairs professionals and the pharmaceutical industry, this moment highlights a fundamental principle: accelerated innovation cannot replace robust evidence generation