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The glucose-lowering capacity of SGLT2 inhibitors is blood glucose-dependent [32], which minimizes hypoglycemic events

97 Finally, these medications have shown to improve cardiorespiratory fitness

Common short-term effects include: Nausea after meals Vomiting, especially after large or oily meals Loose stools or diarrhoea Constipation Abdominal discomfort Reduced hunger Early fullness Mild headache Tiredness Dizziness Low blood sugar, mainly in people with diabetes who also take insulin or sulfonylurea medicines Dehydration if vomiting or diarrhoea is frequent Food aversions or dislike for certain smells Mild symptoms can often be managed with diet changes and hydration

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therefore, speculation continues regarding GLP-1s involvement in skin repair or pathology through chaperone mechanisms