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A third incretin-based approach is tirzepatide, a dual agonist of GLP-1R and glucose-dependent insulinotropic polypeptide receptor (GIPR), which achieves greater HbA1c reduction and weight loss compared with GLP-1RAs alone
P = .30)
Since then, its been one of the top prescribed medications for type II diabetes
Efficacy and Safety of Phentermine/Topiramate in Adults With Overweight or Obesity: A Systematic Review and MetaAnalysis
