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At week 40, mean change in systolic and diastolic blood pressure was 6.1 to 12.6 mm Hg and 2.0 to 4.5 mm Hg for tirzepatide groups and 1.7 mm Hg and 2.1 mm Hg for the placebo group (eTable 7 in Supplement 2)

The SURMOUNT-3 study raised some concerns regarding attrition bias due to missing outcome data

The Food Drug, and Cosmetic Act (FDCA) defines shortage as a period of time when the demand or projected demand for the drug within the United States exceeds the supply of the drug. 21 U.S.C. 356c

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Semaglutide functions by imitating GLP-1, helping to control blood sugar and appetite