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Between June and July 2025, when the formulary change was implemented, switching from AOM tirzepatide increased, while patients with an active supply of AOM semaglutide showed stable or even slightly reduced switching during the same period, consistent with its designation as the preferred option

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According to a 2024 study in the New England Journal of Medicine , weight loss was not the only upside of the medication

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[2] Recent advances in pharmacotherapy have introduced GLP-1 receptor agonists (GLP-1 RAs) and gastric inhibitory polypeptide (GIP) receptor agonists, which have shown promise in both weight loss and CVD prevention