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Conclusion Psychiatric adverse events comprised only 1.2% of the total reports for semaglutide, liraglutide, and tirzepatide

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Weeks four through eight: dose increase drives accelerated results When you advance from 0.25mg to 0.5mg at week four, expect a noticeable step change in appetite suppression within days

For example, a patient with type 2 diabetes on GLP-1 scheduled for hip replacement may continue the agent until 1 to 2 weeks pre-op if weight loss is modest, but stop earlier if gastroparesis or severe nausea is present