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In one such study, Joo et al found no difference between 692 GLP-1RA and 289 SGLT-2I users in DR by clinical worsening, using ICD-10 codes, or by need for procedures after propensity score matching across baseline variables

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Individuals treated with GLP-1 medications exhibited a 7% reduction in risk for obesity-related cancer and an 8% reduction in all-cause mortality, results of a target trial emulation study showed

doi: 10.3389/fendo.2017.00047 123 GibbsJYoungRCSmithGP

Future clinical trials should aim to distinguish the direct analgesic effects of GLP-1RAs from their metabolic benefits and explore their broader applications in pain conditions