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What to Expect When Staying on GLP-1 Long-Term Staying on GLP-1 long-term doesnt always mean a high dose forever

Followed for 12 months

Rev Clin Esp

( 10.1007/s00403-010-1080-1) [DOI] [PMC free article] [PubMed] [Google Scholar] 13.Chang G, Chen B, Zhang L

In addition to its local gut functions, the gut microbiota also produces bioactive metabolites, such as short-chain fatty acids (SCFAs), lipopolysaccharides (LPS), secondary bile acids, and generates precursors of uremic toxins, targeting systemic distant organs such as the liver, kidney, and cardiovascular system [5, 6]

The three glucose-lowering medications are common second-line therapies recommended by the guidelines [8, 9]
