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We further restricted our cohort to non-diabetic, obese men by excluding men with a prior diabetes mellitus diagnosis, a hemoglobin A1c>6.5%, or having ever received insulin or metformin

Individual outcomes vary based on metabolic biomarkers, genetic factors in GLP-1 signaling pathways, and lifestyle adherence

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Many employees turn to GLP-1 drugs after other weight loss treatments have proven ineffective.

GLP-1RA are guideline-endorsed for patients with T2DM and high CV/renal risk irrespective of HbA1c