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Description
The tail vein was catheterized to allow injection of the fluorescent dye
The glucagon arm activates liver fat-burning, defends resting metabolic rate against dropping, and amplifies the heart-rate climb
Unlike injectable semaglutide formulations (such as Ozempic or Wegovy), Rybelsus is taken as a tablet, making it the first oral GLP-1 receptor agonist available
Pregnancy: Use only if clearly needed
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GIP receptor agonism is hypothesised, based on preclinical and early clinical data, to complement GLP-1 effects on insulin secretion and may influence adipose tissue metabolism, though the precise contribution in humans remains an area of active investigation
