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Modelling sample and observational level variability improves power in RNA-seq analyses

Metabolic and Lipid Effects Study (JCEM, 2026) Study Title: Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes Link: [academic.oup.com] Key Findings: Demonstrated improvements in biomarkers associated with insulin resistance and cardiovascular risk

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In research and clinical settings, histamine is widely studied as a biomarker for allergic and inflammatory conditions