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doi: 10.1016/S0140-6736(21)02188-7 74 BattelinoTBergenstalRMRodrguezAFernndez LandLBrayRTongZet al

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Milder side effects, like nausea, typically reduce within a couple of weeks

If you miss 2 or more doses, consult with your doctor for a dosage adjustment

Together, these findings necessitate further investigations to ascertain whether coordinated inhibition of NMDA receptors in GLP-1 receptor neurons modulates neuronal activity beyond canonical feeding regions, such as the mesolimbic dopaminergic reward pathway

Importantly, many of the earlier concerns were derived from animal models or spontaneous adverse event reporting systems, which are limited by their observational nature and lack of control groups (Davies et al., 2021