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575 Similarly, the loss of mitochondrial complex I leads to a decrease in the ratio of NAD + /NADH and can inhibit the activity of Sirt3, thereby enhancing the protein acetylation and mPTP sensitivity
The tablet should be taken once daily on an empty stomach with no more than about 120 mL (4 ounces) of plain water, and patients should wait at least 30 minutes before eating, drinking, or taking other oral medications
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