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GLP-1 RAs are acknowledged for their role in maintaining glucose homeostasis and exerting a range of broader biological effects, including cardioprotective properties

Oral GLP-1 programs remained minimal until the late 2000s, then began rising meaningfully post-2018with the most visible step-up in the last few years: 10 oral programs in 2022, and 11 each in 2024 and 2025

But culturally, it also arrived at exactly the right moment

Because the heart is a muscle, it also is necessary for regular heartbeats

Patients with poorly controlled depression, active suicidal ideation, or recent medication changes may not be ideal candidates for initiating weight loss therapy until their mental health is stabilized

Use-it-or-lose-it means that any funds in your FSA that are not used by the end of the fiscal year may be forfeited