glp-1/gip vs glp-1 The Effects of Dual Receptor Agonism on Glucagon Secretion—A Review Understanding GLP-1 vs. GIP Medications:
Description
GLP-1 agonists including semaglutide slow gastric emptying, which can intensify alcohol effects and increase nausea risk

If you're pregnant, suspect you may be pregnant, or are planning to become pregnant, don't start GLP-1 treatment
Cubillos J, Tse C, Chan VW, Perlas A

That damage occurs mostly in the eyes, nerves, and kidneys

While these are not contraindications to the wellbutrin and tirzepatide combination specifically, autoimmune conditions add variables that require individualized risk assessment and more frequent monitoring
The most rigorous bone-specific human RCT to date found statistically significant reductions in hip and lumbar spine bone density within 52 weeks in a specific study population
