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The SURMOUNT-4 trial gave people 36 weeks of open-label tirzepatide titrated to their maximum tolerated dose (10 or 15 mg), then randomized them to either continue or switch to placebo

Contemp Clin Trials Commun 28:100944 Minozzi S, Dwan K, Borrelli F, Filippini G (2022) Reliability of the revised Cochrane risk-of-bias tool for randomised trials (RoB2) improved with the use of implementation instruction

These can be customized for strength, dosing schedule, and delivery method

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Note that 75 grams of sugar is around cup of granulated sugar

Retatrutide: The Triple Agonist Approach Retatrutide takes the multi-receptor concept further by targeting three distinct receptor systems simultaneously