glp-1 receptor agonists effects on cardiovascular risk reduction Frontiers Cardiovascular Protective Properties of GLP-1

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Outcomes Figure 1 shows the network of comparisons for the outcomes

Eli Lilly's oral GLP-1 pill may help people with Type 2 diabetes lose 'significant' weight, study finds Drugmaker Eli Lilly says its daily oral GLP-1 pill may help people who have obesity and people with Type 2 diabetes lose approximately 23 pounds or more than 10% of their body weight on average, according to new data released Tuesday morning

PMID: 23684623

The degree of weight loss was independently associated with statistically significant improvements in all NASH-related histologic parameters and provides strong evidence that weight loss is an effective treatment for NAFLD

In conclusion, GLP-1R activation triggers a series of complex physiological responses in pancreatic -cells that work together to increase insulin secretion, inhibit -cell apoptosis and stimulate proliferation, protect -cells and ultimately regulate blood glucose