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Description
In a person with type 2 diabetes, the liver may release excess glucose even when blood glucose levels are already elevated, compounding the hyperglycemia
[DOI] [PubMed] [Google Scholar] Wilmen A, Van Eyll B, Goke B, Goke R
The phase 2 trial measured outcomes at 24 and 48 weeks for a reason
For semaglutide, monitoring is more straightforward

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In PIONEER 4, the glycemic effects of oral semaglutide and comparators were investigated in patients with and without SGLT2i as background therapy
