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Semaglutide 2.4 mg reduced the risk of kidney events in people with obesity and without T2D

The art of tissue-specific and disease-specific dosing may emerge in the not-too-distant future: Rather than using the current pharmacologic doses of GLP-1s to soak receptors throughout the body, we may learn how to apply much more tailored brush strokes to effectively treat, say, dementia or rheumatoid arthritis

GLP-1 medications may not be appropriate for all individuals

They solved two major challenges: optimal binding to the GLP-1 receptor and particularly extended circulating half-life, making it both effective and reasonably tolerable

SCFA are able to modulate cytokine and chemokine expression of immune cells and adipocytes (190)

When food stays in your stomach longer, you feel full longer