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Description
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for the treatment of type 2 diabetes and obesity, may modulate pathways associated with the hallmarks of aging
In conclusion, GLP-1 RAs are an intriguing multitarget treatment option for people with NDs, and future research should focus on optimizing treatment for clinical trials, evolved agonists that can penetrate the central nervous system (CNS), and combination therapies.
We also estimated 10-year CVD risks utilizing the BMI-based Framingham CVD risk scores
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Oseltamivir (Tamiflu) was discovered by Gilead in 1995, patented in 1996, subsequently transferred to Roche, and approved by the FDA in 1999
21. Edo GI et al
