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Similar content being viewed by others Background Glucagon-like peptide-1 (GLP-1) receptor agonists, exenatide, lixisenatide, liraglutide, dulaglutide and semaglutide, are among the recent subcutaneous treatment options that provide better glycemic improvement and weight loss in patients with type 2 diabetes according to the current guidelines [1, 2]

We discuss potential side effects, such as nausea and gastrointestinal discomfort, and tailor the dosage and treatment plan accordingly

Semaglutide does show up in blood work if specifically tested, and so does tirzepatide , so inform all your providers about every medication you are taking

Over-the-counter antidiarrheal medications like loperamide or fiber supplements and osmotic laxatives may be appropriate for short-term use, but you should discuss these options with your healthcare provider before starting them to ensure safe and effective management

This mechanism explains why some patients experience heartburn or acid regurgitation shortly after starting GLP-1 therapy