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Additional populations requiring careful consideration include patients with kidney disease (specific recommendations vary by medication), those with a history of diabetic retinopathy (particularly if rapidly improving glycemic control), and individuals with active or recent malignancy

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Contact your GP or diabetes team if you experience persistent side effects, have concerns about your treatment, or if your blood glucose control deteriorates whilst using GLP-1 therapy

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The research literature supports 28 days as the conservative recommendation with a reasonable safety margin

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