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41:2229-2235 [PMC free article: PMC6150424] [PubMed: 30072400] 306

These primary actions follow directly from the distribution of GLP-1 receptors in out bodies

Pan, H.-C

Therefore, it is necessary to establish personalized discontinuation schedules and fasting protocols that reflect the pharmacologic properties of each drug, duration of therapy, and gastrointestinal status of individual patients

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However, GLP-1 can act as a helpful addition especially for patients who: Have obesity or are overweight Have type 2 diabetes or metabolic syndrome Need improvements in multiple metabolic risk factors (not just cholesterol) Who Benefits Most The cholesterol and lipid benefits of GLP-1 tend to be greater in: People who lose significant weight on it Those with elevated triglycerides to start Patients with insulin resistance or type 2 diabetes Individuals implementing lifestyle changes (diet, physical activity, etc.) alongside medication What to Expect & Important Things to Know Timeframe : Changes in lipid levels usually show up over months not immediately