glp-1 receptor agonist medicines Agonists: An Alternative for Rapid-Acting Insulin? Frontiers | Exploring the multifaceted
Description
Jama (2019) 321(15):14578

Stimulation of -cell proliferation secondary to stimulating GLP-1R is usually only observed in young animals (during periods characterized by preserved proliferative capacity), and not in older rodents [548]

The appetite suppression they produce is significant
In addition, the glucagon part may also help reduce fat in the liver, which is important for NASH studies

However, conflicting evidence highlights context-dependent risks, such as early DR worsening in poorly controlled glycemic states

19 KhanSSNingHWilkinsJTAllenNCarnethonMBerryJDet al
