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doi: 10.1038/nrd.2017.16 148 NajjarS.PearlmanD

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Using L cells and mice fed on an HFD, we show that purified P9 alone is sufficient to induce GLP-1 secretion and brown adipose tissue thermogenesis

However, the development of beloranib was halted following the deaths of two patients from pulmonary embolism during the trial

So, the health coaches I found to be way more up on this than the doctors