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Description
The physiological roles of GLP-1 are more than sufficient for it to be targeted for the development of anti-diabetic and anti-obesity medication [2]
McGuire DK, Alexander JH, Johansen OE, Perkovic V, Rosenstock J, Cooper ME, Wanner C, Kahn SE, Toto RD, Zinman B, Baanstra D, Pfarr E, Schnaidt S, Meinicke T, George JT, von Eynatten M, Marx N, Cahn A
Glucagon-like peptide-1 receptors in the brain: controlling food intake and body weight
Secnik, J
f , Change in body weight
In animal experiments, particularly in mouse models, GDF-15 enhances satiety and reduces food intake through its action on the central nervous system
