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Amputation of the toe and mid-foot were most frequent (21 out of 28 JARDIANCE 10 mg treated patients with lower limb amputations), and some involving above and below the knee

And while the 41-year-old (real name Jason Bradley DeFord ) has been dedicated to his weight loss journey in recent yearshaving already shed, by his estimation, nearly 300 poundshe revealed he suffered a setback not long after landing the cover of Mens Health in the fall

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doi: 10.1016/j.nut.2012.01.016

doi: 10.3389/fnbeh.2026.1805953 Received 06 February 2026 Revised 13 March 2026 Accepted 13 March 2026 Published 13 April 2026 Volume 20 - 2026 Edited by Emmanuel Darcq, Institut National de la Sant et de la Recherche Mdicale (INSERM), France Reviewed by Zhe Zhao, Max Planck Florida Institute for Neuroscience (MPFI), United States Madhawi Aldhwayan, King Saud University, Saudi Arabia Updates Copyright 2026 OConnor