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Some people may begin to experience improvements in pain, swelling, tenderness, or stiffness within 24 to 72 hours
Fontes: Jastreboff, Ania M et al
Ligand Pioglitazone on Platelet Aggregation and Arterial Thrombus Formation
And I think it's a very reassuring answer
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Your individual timeline depends on your metabolic needs, response to treatment, and clinical goals
