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Selective kappa opioid antagonism ameliorates anhedonic behavior: Evidence from the Fast-Fail Trial in mood and anxiety spectrum disorders (FAST-MAS)

La inhibicin resetea el sistema reduciendo el umbral de saturacin para la glucosuria de manera que sta se inicie con niveles de glicemia 60-80mg menores (100mg/dl), con lo que aumenta la excrecin urinaria de glucosa en 60-80g/da102

RyR2: the type 2 ryanodine receptor

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