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[6] [7] Important safety considerations include contraindications for patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), and warnings regarding pancreatitis, gallbladder disease, and diabetic retinopathy complications

Dehydration and Electrolyte Imbalance : Gastrointestinal side effects, particularly nausea, vomiting, and diarrhea, can lead to dehydration and electrolyte disturbances that manifest as fatigue