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Jastreboff and colleagues (NEJM, 2023) reported substantial body-weight reduction in obesity research populations, and Rosenstock and colleagues (Lancet, 2023) documented glycemic and weight effects in type-2 diabetes research populations

Also, though Semaglutide by injection is available in therapeutic doses starting at .5mg, they only tested the 2.4mg weight loss dose here (with people taking less only when they couldnt tolerate the target dose.) I wonder if its because thats the dose for which they are pushing for Medicare and insurance coverage right now

If you are someone with modestly increased weight but are otherwise healthy, I think its important that you consider what you might change about your diet and physical activity to promote good health, as opposed to looking for a short-term tool to make the number on the scale go down quickly

Depending on your overall health, some side effects may be more dangerous than the risks of being overweight

while Mounjaro should be refrigerated, it can be kept at room temperature briefly before use

(21) Baseline measurements of P1NP, BMD, and CTX-1 were recorded, and participants were randomized into the semaglutide group to receive 1.0 mg or the placebo group