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However, its future trajectory is far from linear as many uncertainties remain, e.g., acceptance of obesity as a chronic disease, budget impact faced by payers and health systems willingness and ability to pay, the readout of further cardiovascular outcomes trials after the high profile results of 2023s SELECT trial for Wegovy, or new entrants challenging first generation therapies with alternative mechanisms of action (MoA) to address shortcomings such as gastrointestinal tolerability, current drugs being injectables, or the durability and quality of weight loss which distinguishes between fat and lean body mass

Much hyped online, FDA-approved diabetes wonder drugs, now touted for treating obesity

A lawsuit was filed against the drug makers of Ozempic and Mounjaro after a woman claimed she experienced severe side effects like gastroparesis, also known as stomach paralysis