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Other approaches followed the strategy to couple (modified) GLP-1 to large proteins such as an immunoglobulin Fc fragment (dulaglutide or efpeglenatide) or albumin (albiglutide)

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Patients with kidney disease can typically use semaglutide without dose adjustment, but should be monitored for dehydration which could worsen kidney function

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Abstract Objective This study aimed to systematically review the existing literature to summarize the incidence and risk factors of post-metabolic and bariatric surgery hypoglycemia (MBSH)

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Doses ranging from 0.25 mg to 1.0 mg daily have been investigated

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