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However, these agents increase risk of intra-operative pulmonary aspiration according to a case report secondary to delayed emptying and presence of gastric residues despite fasting (108, 108) To prevent these events, the recent recommendations from the American Society of Anesthesiology guidelines suggest discontinuing GLP-1 receptor agonists 1 day prior in patients on daily dosing and 1 week prior in patients on weekly injection dosing (108)

Even mild but persistent symptoms can lead to treatment discontinuation, particularly in non-diabetic individuals using these agents primarily for weight management, who may have lower thresholds for tolerability than diabetic patients

Liraglutide was generally well tolerated with predominantly mild gastrointestinal adverse events

Managing Nausea When nausea occurs despite your prevention efforts, many of these strategies can help manage symptoms: Over-the-Counter Remedies: Antacids: Medications like Tums or Rolaids can help neutralize stomach acid, which may improve nausea for some individuals

[DOI] [PubMed] [Google Scholar] 77.Palmer B.F., Clegg D.J

www.cdc.gov/chronicdisease/ resources/publications/factsheets/diabetes-prediabetes.htm