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Mitochondrial dysfunction, characterized by impaired -oxidation capacity and increased ROS formation, fuels the aberrant ROS production [137]

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Sherwin et al (2023) : Influence of semaglutide use on the presence of residual gastric solids on gastric ultrasound: a prospective observational study in volunteers without obesity recently started on semaglutide Twenty patients were given semaglutide or a control, with the following results after an 8-hour fasting period: Supine position: 70% of semaglutide participants and 10% of control participants had solids present on gastric ultrasound

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These cardiovascular benefits likely stem from a combination of weight reduction, improved insulin sensitivity, and direct vascular effects of the therapeutic compound

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