tirzepatide surmount 3 once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase trial Tirzepatide and health‐related quality of

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Nausea, constipation, and appetite suppression occur with both formulations at similar overall rates when doses are matched for potency

Disclosures: Rohit Loomba, MD, is a consultant or advisory board member for Aardvark Therapeutics, Altimmune, Anylam/Regeneron, Amgen, Arrowhead Pharmaceuticals, AstraZeneca, Bristol-Myer Squibb, CohBar, Eli Lilly, Galmed, Gilead, Glympse bio, Hightide, Inipharma, Intercept, Inventiva, Ionis, Janssen Inc., Madrigal, Metacrine, Inc., NGM Biopharmaceuticals, Novartis, Novo Nordisk, Merck, Pfizer, Sagimet, Theratechnologies, 89 bio, Terns Pharmaceuticals and Viking Therapeutics

Common side effects Nausea Vomiting Diarrhea Stomach pain Decreased appetite Risk of low blood sugar Constipation Serious side effects of tirzepatide can include pancreatitis (inflammation of the pancreas), gallbladder problems, kidney problems, and severe allergic reactions